Dr Anne Donnet

Hôpital de la Timone
264 Rue Saint-Pierre
13385Marseille Cedex 5

Pain Department

The department is dedicated to evaluate and treat pain. It helps patients through diagnosis, evaluations of bio-psycho-social chronic pain syndromes, multidisciplinary follow-up,  multi-professional approach and individualized care.


 Publications of the pain Center aim :

  • Clinical characteristics of patients with cluster headache evolving on chronic modality
  • Safety evaluation of cardiac patients with cluster headache and treated with high doses of verapamil
  • Clinical characteristics of patients with headache hypnic
  • Monitoring patients with idiopathic intracranial hypertension treated with venous stent
  • Thinking about the pathophysiology of stress headaches.

Recent research works focus on clinical trials of new treatments crisis of migraine, clinical trials of surgical treatment of drug-resistant cluster headaches and labeled idiopathic headache origins.

Work Packages

Discover the main work modules of Inovpain FHU.

Research Teams

Several academic research teams participate in the INOVPAIN project.

Want to know more about pain ?

Find informations by visiting these websites.


Latetest scientific articles about chronic pain.

Recent works

  1. Donnet, A, Emery, C, Aly, S, Allaf, B, Cayre, F, Mahieu, N et al.. Migraine burden and costs in France: a nationwide claims database analysis of triptan users. J Med Econ. 2019; :1-9. doi: 10.1080/13696998.2019.1590841. PubMed PMID:30836035 .
  2. Redon, S, Graillon, N, Régis, J, Donnet, A. First Bite Syndrome After Trigeminal Radiosurgery: Case Report and Pathophysiology. Headache. 2018;58 (10):1680-1681. doi: 10.1111/head.13449. PubMed PMID:30431167 .
  3. Donnet, A, Redon, S. Cyclic Vomiting Syndrome in Children. Curr Pain Headache Rep. 2018;22 (4):30. doi: 10.1007/s11916-018-0684-6. PubMed PMID:29556858 .
  4. de Rijk, P, Resseguier, N, Donnet, A. Headache Characteristics and Clinical Features of Elderly Migraine Patients. Headache. 2018;58 (4):525-533. doi: 10.1111/head.13247. PubMed PMID:29235107 .
  5. Redon, S, Donnet, A. Sneezing in Primary Headaches With Cranial Autonomic Symptoms: Pathophysiological Considerations. A Series of Case Reports. Headache. 2018;58 (2):298-303. doi: 10.1111/head.13242. PubMed PMID:29226314 .
  6. Borius, PY, Garnier, SR, Baumstarck, K, Castinetti, F, Donnet, A, Guedj, E et al.. An Open-Label, Analgesic Efficacy and Safety of Pituitary Radiosurgery for Patients With Opioid-Refractory Pain: Study Protocol for a Randomized Controlled Trial. Neurosurgery. 2018;83 (1):146-153. doi: 10.1093/neuros/nyx363. PubMed PMID:28973682 .
  7. Borius, PY, Tuleasca, C, Muraciole, X, Negretti, L, Schiappacasse, L, Dorenlot, A et al.. Gamma Knife radiosurgery for glossopharyngeal neuralgia: A study of 21 patients with long-term follow-up. Cephalalgia. 2018;38 (3):543-550. doi: 10.1177/0333102417698961. PubMed PMID:28952337 .
  8. Redon, S, Mareau, C, Guedj, E, Donnet, A. Cyclic Vomiting Syndrome in Adults and Children: A Hypothesis. Headache. 2017;57 (6):943-951. doi: 10.1111/head.13108. PubMed PMID:28488756 .
  9. Fontaine, D, Blond, S, Lucas, C, Regis, J, Donnet, A, Derrey, S et al.. Occipital nerve stimulation improves the quality of life in medically-intractable chronic cluster headache: Results of an observational prospective study. Cephalalgia. 2017;37 (12):1173-1179. doi: 10.1177/0333102416673206. PubMed PMID:27697849 .
  10. Thorlund, K, Toor, K, Wu, P, Chan, K, Druyts, E, Ramos, E et al.. Comparative tolerability of treatments for acute migraine: A network meta-analysis. Cephalalgia. 2017;37 (10):965-978. doi: 10.1177/0333102416660552. PubMed PMID:27521843 .
  11. Régis, J, Tuleasca, C, Resseguier, N, Carron, R, Donnet, A, Yomo, S et al.. The Very Long-Term Outcome of Radiosurgery for Classical Trigeminal Neuralgia. Stereotact Funct Neurosurg. 2016;94 (1):24-32. doi: 10.1159/000443529. PubMed PMID:26882097 .
  12. Donnet, A, Leger, JM. [Suicide headache]. Presse Med. 2015;44 (11):1170. doi: 10.1016/j.lpm.2015.11.001. PubMed PMID:26615084 .
  13. Donnet, A, Valade, D, Fontaine, D. [Cluster headache treatment]. Presse Med. 2015;44 (11):1188-92. doi: 10.1016/j.lpm.2015.10.003. PubMed PMID:26547676 .
  14. Donnet, A. [Pathophysiology of cluster headache]. Presse Med. 2015;44 (11):1171-5. doi: 10.1016/j.lpm.2015.09.011. PubMed PMID:26470883 .
  15. Régis, J, Tuleasca, C, Resseguier, N, Carron, R, Donnet, A, Gaudart, J et al.. Long-term safety and efficacy of Gamma Knife surgery in classical trigeminal neuralgia: a 497-patient historical cohort study. J. Neurosurg. 2016;124 (4):1079-87. doi: 10.3171/2015.2.JNS142144. PubMed PMID:26339857 .
  16. Donnet, A. Transient Global Amnesia Triggered by Migraine in a French Tertiary-Care Center: An 11-Year Retrospective Analysis. Headache. 2015;55 (6):853-9. doi: 10.1111/head.12545. PubMed PMID:25877480 .
  17. Tuleasca, C, Carron, R, Resseguier, N, Donnet, A, Roussel, P, Gaudart, J et al.. Decreased Probability of Initial Pain Cessation in Classic Trigeminal Neuralgia Treated With Gamma Knife Surgery in Case of Previous Microvascular Decompression: A Prospective Series of 45 Patients With >1 Year of Follow-up. Neurosurgery. 2015;77 (1):87-94; discussion 94-5. doi: 10.1227/NEU.0000000000000739. PubMed PMID:25812065 .
  18. Braunstein, D, Donnet, A, Pradel, V, Sciortino, V, Allaria-Lapierre, V, Lantéri-Minet, M et al.. Triptans use and overuse: A pharmacoepidemiology study from the French health insurance system database covering 4.1 million people. Cephalalgia. 2015;35 (13):1172-80. doi: 10.1177/0333102415570497. PubMed PMID:25667299 .
  19. Tuleasca, C, Carron, R, Resseguier, N, Donnet, A, Roussel, P, Gaudart, J et al.. Repeat Gamma Knife surgery for recurrent trigeminal neuralgia: long-term outcomes and systematic review. J. Neurosurg. 2014;121 Suppl :210-21. doi: 10.3171/2014.8.GKS141487. PubMed PMID:25434955 .
  20. Tuleasca, C, Carron, R, Resseguier, N, Donnet, A, Roussel, P, Gaudart, J et al.. Multiple sclerosis-related trigeminal neuralgia: a prospective series of 43 patients treated with gamma knife surgery with more than one year of follow-up. Stereotact Funct Neurosurg. 2014;92 (4):203-10. doi: 10.1159/000362173. PubMed PMID:25011487 .
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